Incretins
DA-1726
Oxyntomodulin analog; GLP-1 and glucagon receptor dual agonist with a 3:1 GLP1R to GCGR potency ratio
MetaVia's weekly oxyntomodulin analog acts on GLP-1 and glucagon receptors. An interim Phase 1 Part 3B analysis showed 13.5% placebo-adjusted weight loss and a 68% placebo-adjusted cut in liver fat at Day 109, by the company's account.